5/7/2023 0 Comments After 9/11 by Sid Jacobson![]() ![]() There was no statistically significant difference between Groups A ( n = 79) and C ( n = 27) for new respiratory signs post-melarsomine ( P = 0.73). One hundred fifty-seven dogs with asymptomatic or mild heartworm disease at presentation were included. New respiratory signs and gastrointestinal (GI) signs were compared between dogs receiving SID or BID doxycycline. Respiratory complications were defined as respiratory signs requiring additional treatment, and were statistically compared for Groups A and C. Treatments that fell outside these ranges formed two additional treatment groups (Groups B and D). ![]() Dogs were retrospectively grouped based on the shelter’s current protocol (M1 on day 14 Group A) and the AHS protocol (M1 on day 60 Group C), allowing a week on either side of the target M1 day. MethodsĪs compared with the AHS protocol, the shelter protocols utilized doxycycline 10 mg/kg once daily (SID) or twice daily (BID), and varied the time from initiation of doxycycline (day 1) to the first melarsomine injection (M1). This retrospective study evaluated modified three-dose melarsomine treatment protocols in a shelter setting and compared them to the American Heartworm Society (AHS)-recommended protocol. ![]()
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